| Catalog#: |
MK0115C |
| Product Name: |
Recombinant Cynomolgus CD38 protein, His-tagged |
| Product Overview: |
Recombinant Cynomolgus CD38 (Leu44-Ile301) protein was fused to His-tag at C-terminus and expressed in human 293 cells (HEK293 cells). |
| Description: |
CD38, also known as ADP-ribosyl cyclase, is a transmembrane glycoprotein comprising two to four N-linked oligosaccharide chains containing sialic acid residues. It is expressed on the surface of immune cells including CD4+, CD8+, B and natural killer cells. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. CD38 functions in cell adhesion, signal transduction and calcium signaling. Through its production of cyclic ADP-ribose |
| Source: |
HEK293 cells |
| Species: |
Cynomolgus |
| Tag: |
His |
| Formulation: |
Lyophilized from 0.22 μm filtered solution in 50 mM MES, 100 mM NaCl, pH6.5, 10% trehalose. |
| Protein length: |
Leu44 -Ile 301 |
| Purity: |
>95% as determined by SDS-PAGE. |
| Storage: |
Store under sterile conditions at -20°C to -80°C. Avoid repeated freeze-thaw cycles. |
| Reconstitution: |
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 mg/mL. Centrifuge the vial at 4°C before opening to recover the entire contents. |
| Molecular Mass: |
The protein has a calculated MW of 31.8 kDa. The protein migrates as 38-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
| Endotoxin: |
Less than 1.0 EU per μg as determined by the LAL method. |
| Notes: |
Research Use Only. Not for use in clinical procedures.Aoid repeated freeze-thaw cycles. |
