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Recombinant Cynomolgus CD38 protein, His-tagged

Product Information
Catalog#:  MK0115C
Product Name:  Recombinant Cynomolgus CD38 protein, His-tagged
Product Overview:  Recombinant Cynomolgus CD38 (Leu44-Ile301) protein was fused to His-tag at C-terminus and expressed in human 293 cells (HEK293 cells).
Description:  CD38, also known as ADP-ribosyl cyclase, is a transmembrane glycoprotein comprising two to four N-linked oligosaccharide chains containing sialic acid residues. It is expressed on the surface of immune cells including CD4+, CD8+, B and natural killer cells. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. CD38 functions in cell adhesion, signal transduction and calcium signaling. Through its production of cyclic ADP-ribose
Source:  HEK293 cells
Species:  Cynomolgus
Tag:  His
Formulation:  Lyophilized from 0.22 μm filtered solution in 50 mM MES, 100 mM NaCl, pH6.5, 10% trehalose.
Protein length:  Leu44 -Ile 301
Purity:  >95% as determined by SDS-PAGE.
Storage:  Store under sterile conditions at -20°C to -80°C. Avoid repeated freeze-thaw cycles.
Reconstitution:  It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 mg/mL. Centrifuge the vial at 4°C before opening to recover the entire contents.
Molecular Mass:  The protein has a calculated MW of 31.8 kDa. The protein migrates as 38-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin:  Less than 1.0 EU per μg as determined by the LAL method.
Notes:  Research Use Only. Not for use in clinical procedures.Aoid repeated freeze-thaw cycles.
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