| Classification: |
Mouse Proteins |
| Catalog#: |
MK1033M |
| Product Name: |
Mouse IL-23 alpha & IL-12 beta Protein, His-tagged |
| Description: |
Interleukin-23 (IL-23) is a cytokine that plays a key role in the differentiation and activation of T-helper 17 (Th17) cells. It is involved in autoimmune and inflammatory diseases, particularly psoriasis and Crohn's disease. |
| Source: |
HEK293 cells |
| Species: |
Mouse |
| Tag: |
His |
| Formulation: |
1× PBS, pH 7.4 |
| Proteinlength: |
Val22-Ala196 & Met23-Ser335 |
| Purity: |
Mouse IL-23 alpha & IL-12 beta protein, His tag on SDS-PAGE under non-reducing (NR) and reducing (R) conditions. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95.0%. |
| Storage: |
For long term storage, the product should be stored at lyophilized state at -20 °C or lower. |
| Reconstitution: |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water. |
| Molecular Mass: |
112.52 kDa |
| Stability: |
Upon receiving, the product remains stable for 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. |
| Endotoxin: |
＜0.001 EU/μg |
| Concentration: |
1 mg/mL |
| Quality Control: |
Immobilized mouse IL-23 alpha & IL-12 beta protein (His tag) binds to Ustekinumab with an EC50 of 0.008575 μg/mL. |
| Notes: |
Research Use Only. Not for use in clinical procedures. |
