| Classification: |
Mouse Proteins |
| Catalog#: |
MK1025M |
| Product Name: |
Mouse EGFR Protein, His-tagged |
| Description: |
Epidermal growth factor receptor (EGFR), also known as HER1, is a receptor tyrosine kinase involved in cell growth, differentiation, and survival. It is a critical target in cancer therapies, particularly in tumors with EGFR mutations. |
| Source: |
HEK293 cells |
| Species: |
Mouse |
| Tag: |
His |
| Formulation: |
100 mM Pro-Ac, 20 mM Arg, pH 5 |
| Proteinlength: |
Leu25-Ser647 |
| Purity: |
Mouse EGFR protein, His tag on SDS-PAGE under reducing (R) conditions. The purity of the protein is greater than 85.0%. |
| Storage: |
For long term storage, the product should be stored at lyophilized state at -20 °C or lower. |
| Reconstitution: |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water. |
| Molecular Mass: |
70.13 kDa |
| Stability: |
Upon receiving, the product remains stable for 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. |
| Endotoxin: |
＜0.001 EU/μg |
| Concentration: |
1 mg/mL |
| Quality Control: |
Immobilized cetuximab binds to mouse EGFR protein (His tag) with an EC50 of 0.4170 μg/mL. |
| Notes: |
Research Use Only. Not for use in clinical procedures. |
