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Mouse B7-H1/PD-L1/CD274 Protein, Fc-tagged

Product Information
Classification:  Mouse Proteins
Catalog#:  MK1015M
Product Name:  Mouse B7-H1/PD-L1/CD274 Protein, Fc-tagged
Description:  PD-L1 (B7-H1) is a key immune checkpoint protein that inhibits T-cell activation, playing a central role in immune evasion by tumors. It is a major target in cancer immunotherapy.
Source:  HEK293 cells
Species:  Mouse
Tag:  Fc
Formulation:  100 mM Pro-Ac, 20 mM Arg, pH 5
Proteinlength:  Phe19-His239
Purity:  Mouse B7-H1 / PD-L1 / CD274 protein, Fc tag on SDS-PAGE under non-reducing (NR) and reducing (R) conditions. The purity of the protein is greater than 85.0%.
Storage:  For long term storage, the product should be stored at lyophilized state at -20 °C or lower.
Reconstitution:  Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
Molecular Mass:  101.94 kDa
Stability:  Upon receiving, the product remains stable for 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C.
Endotoxin:  <0.001 EU/μg
Concentration:  1 mg/mL
Quality Control:  Immobilized mouse B7-H1/PD-L1/CD274 protein (Fc tag) binds to anti-B7-H1/PD-L1/CD274 antibody with an EC50 of 0.03045 μg/mL.
Notes:  Research Use Only. Not for use in clinical procedures.
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