| Product Information | |
|---|---|
| Classification: | Mouse Proteins |
| Catalog#: | MK1015M |
| Product Name: | Mouse B7-H1/PD-L1/CD274 Protein, Fc-tagged |
| Description: | PD-L1 (B7-H1) is a key immune checkpoint protein that inhibits T-cell activation, playing a central role in immune evasion by tumors. It is a major target in cancer immunotherapy. |
| Source: | HEK293 cells |
| Species: | Mouse |
| Tag: | Fc |
| Formulation: | 100 mM Pro-Ac, 20 mM Arg, pH 5 |
| Proteinlength: | Phe19-His239 |
| Purity: | Mouse B7-H1 / PD-L1 / CD274 protein, Fc tag on SDS-PAGE under non-reducing (NR) and reducing (R) conditions. The purity of the protein is greater than 85.0%. |
| Storage: | For long term storage, the product should be stored at lyophilized state at -20 °C or lower. |
| Reconstitution: | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water. |
| Molecular Mass: | 101.94 kDa |
| Stability: | Upon receiving, the product remains stable for 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. |
| Endotoxin: | <0.001 EU/μg |
| Concentration: | 1 mg/mL |
| Quality Control: | Immobilized mouse B7-H1/PD-L1/CD274 protein (Fc tag) binds to anti-B7-H1/PD-L1/CD274 antibody with an EC50 of 0.03045 μg/mL. |
| Notes: | Research Use Only. Not for use in clinical procedures. |
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