| Classification: |
Proteins from other species |
| Catalog#: |
MK0902C |
| Product Name: |
Cynomolgus PD-1 Protein, His-tagged |
| Description: |
Programmed cell death protein 1 (PD-1) is an immune checkpoint receptor that negatively regulates immune cell activity. It is involved in maintaining immune homeostasis and preventing autoimmunity by inhibiting T-cell activation in peripheral tissues. |
| Source: |
HEK293 cells |
| Species: |
Cynomolgus |
| Tag: |
His |
| Formulation: |
1× PBS, pH 7.4 |
| Proteinlength: |
Leu25-Gln167 |
| Purity: |
Cynomolgus PD-1 protein, His tag on SDS-PAGE under reducing (R) conditions. The purity of the protein is greater than 85.0%. |
| Storage: |
For long term storage, the product should be stored at lyophilized state at -20 °C or lower. |
| Reconstitution: |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water. |
| Molecular Mass: |
17.45 kDa |
| Stability: |
Upon receiving, the product remains stable for 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. |
| Endotoxin: |
＜0.001 EU/μg |
| Concentration: |
1 mg/mL |
| Quality Control: |
Immobilized cynomolgus PD-1 protein (His tag) (2 μg/mL) binds to Pembrolizumab with an EC50 of 0.02041 μg/mL. |
| Notes: |
Research Use Only. Not for use in clinical procedures. |
