| Classification: |
Proteins from other species |
| Catalog#: |
MK0893C |
| Product Name: |
Cynomolgus IL-6 R alpha Protein, Fc-tagged |
| Description: |
IL-6 receptor alpha (IL-6Rα) is a subunit of the IL-6 receptor that mediates IL-6 signaling. It is involved in immune regulation and inflammation, making it a target for therapies in autoimmune diseases and cancer. |
| Source: |
CHO cells |
| Species: |
Cynomolgus |
| Tag: |
Fc |
| Formulation: |
1× PBS, pH 6 |
| Proteinlength: |
Leu20-Thr366 |
| Purity: |
Cynomolgus IL-6 R alpha protein, Fc tag on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 85%. |
| Storage: |
For long term storage, the product should be stored at lyophilized state at -20 °C or lower. |
| Reconstitution: |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water. |
| Molecular Mass: |
128.66 kDa |
| Stability: |
Upon receiving, the product remains stable for 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. |
| Endotoxin: |
＜0.001 EU/μg |
| Concentration: |
1 mg/mL |
| Quality Control: |
Immobilized cynomolgus IL-6 R alpha protein (Fc tag) binds to anti-IL-6 R alpha/CD126 antibody with an EC50 of 1.237 μg/mL. |
| Notes: |
Research Use Only. Not for use in clinical procedures. |
