| Classification: |
Proteins from other species |
| Catalog#: |
MK0888C |
| Product Name: |
Cynomolgus IL-5 R alpha/CD125 Protein, mFc-tagged |
| Description: |
IL-5 receptor alpha (IL-5Rα) is a subunit of the IL-5 receptor responsible for mediating IL-5 signaling. It is involved in eosinophil differentiation and activation and is a target for asthma treatments. |
| Source: |
HEK293 cells |
| Species: |
Cynomolgus |
| Tag: |
mFc |
| Formulation: |
0.1 M Na3C6H5O7·2H2O, 0.2 M NaCl, pH 5 |
| Proteinlength: |
Asp21-Gln341 |
| Purity: |
Cynomolgus IL-5 R alpha / CD125 protein, mFc tag on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 85%. |
| Storage: |
For long term storage, the product should be stored at lyophilized state at -20 °C or lower. |
| Reconstitution: |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water. |
| Molecular Mass: |
125.86 kDa |
| Stability: |
Upon receiving, the product remains stable for 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. |
| Endotoxin: |
＜0.001 EU/μg |
| Concentration: |
1 mg/mL |
| Quality Control: |
Immobilized cynomolgus IL-5 R alpha/CD125 protein (mFc tag) binds to anti-IL-5 R alpha/CD125 antibody with an EC50 of 0.05076 μg/mL. |
| Notes: |
Research Use Only. Not for use in clinical procedures. |
