| Product Information | |
|---|---|
| Classification: | Proteins from other species |
| Catalog#: | MK0887C |
| Product Name: | Cynomolgus IL-5 R alpha/CD125 Protein, His-tagged |
| Description: | IL-5 receptor alpha (IL-5Rα) is a subunit of the IL-5 receptor responsible for mediating IL-5 signaling. It is involved in eosinophil differentiation and activation and is a target for asthma treatments. |
| Source: | HEK293 cells |
| Species: | Cynomolgus |
| Tag: | His |
| Formulation: | 1× PBS, pH 8 |
| Proteinlength: | Asp21-Gln341 |
| Purity: | Cynomolgus IL-5 R alpha / CD125 protein, His tag on SDS-PAGE under non-reducing (NR) and reducing (R) conditions. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95.0%. |
| Storage: | For long term storage, the product should be stored at lyophilized state at -20 °C or lower. |
| Reconstitution: | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water. |
| Molecular Mass: | 38.06 kDa |
| Stability: | Upon receiving, the product remains stable for 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. |
| Endotoxin: | <0.001 EU/μg |
| Concentration: | 1 mg/mL |
| Quality Control: | Immobilized cynomolgus IL-5 protein (Fc tag) binds to cynomolgus IL-5 R alpha/CD125 protein (His tag) with an EC50 of 0.20940 μg/mL. |
| Notes: | Research Use Only. Not for use in clinical procedures. |
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