| Product Information | |
|---|---|
| Classification: | Proteins from other species |
| Catalog#: | MK0868C |
| Product Name: | Cynomolgus FcRH5 Protein, Fc-tagged |
| Description: | Fc receptor homolog 5 (FcRH5) is a cell surface receptor that is highly expressed in B-cells, particularly in malignancies such as multiple myeloma. It has potential as a therapeutic target for immune-mediated treatments. |
| Source: | HEK293 cells |
| Species: | Cynomolgus |
| Tag: | Fc |
| Formulation: | 100 mM Pro-Ac, 20 mM Arg, pH 5 |
| Proteinlength: | Ala746-Gly851 |
| Purity: | Cynomolgus FcRH5 protein, Fc tag on SDS-PAGE under non-reducing (NR) and reducing (R) conditions. The gel was stained with Coomassie Blue. The purity of the protein is greater than 85.0%. |
| Storage: | For long term storage, the product should be stored at lyophilized state at -20 °C or lower. |
| Reconstitution: | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water. |
| Molecular Mass: | 74.48 kDa |
| Stability: | Upon receiving, the product remains stable for 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. |
| Endotoxin: | <0.001 EU/μg |
| Concentration: | 1 mg/mL |
| Quality Control: | Immobilized cynomolgus FcRH5 protein (Fc tag) binds to FcRH5-Cevostamab-L2 with an EC50 of 0.03668 μg/mL. |
| Notes: | Research Use Only. Not for use in clinical procedures. |
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