| Classification: |
Proteins from other species |
| Catalog#: |
MK0866C |
| Product Name: |
Cynomolgus EGFR Protein, Fc-tagged |
| Description: |
Epidermal growth factor receptor (EGFR), also known as HER1, is a receptor tyrosine kinase involved in cell growth, differentiation, and survival. It is a critical target in cancer therapies, particularly in tumors with EGFR mutations. |
| Source: |
HEK293 cells |
| Species: |
Cynomolgus |
| Tag: |
Fc |
| Formulation: |
1× PBS, pH 6 |
| Proteinlength: |
Leu25-Ser645 |
| Purity: |
Cynomolgus EGFR protein, Fc tag on SDS-PAGE under reducing (R) conditions. The purity of the protein is greater than 85.0%. |
| Storage: |
For long term storage, the product should be stored at lyophilized state at -20 °C or lower. |
| Reconstitution: |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water. |
| Molecular Mass: |
189.5 kDa |
| Stability: |
Upon receiving, the product remains stable for 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. |
| Endotoxin: |
＜0.001 EU/μg |
| Concentration: |
1 mg/mL |
| Quality Control: |
Immobilized cynomolgus EGFR protein (Fc tag) binds to cetuximab with an EC50 of 0.02499 μg/mL. |
| Notes: |
Research Use Only. Not for use in clinical procedures. |
