| Product Information | |
|---|---|
| Classification: | Proteins from other species |
| Catalog#: | MK0859C |
| Product Name: | Canine PDCD1/PD-1/CD279 Protein, His-tagged |
| Description: | Programmed cell death protein 1 (PD-1) is an immune checkpoint receptor that negatively regulates immune cell activity. It is involved in maintaining immune homeostasis and preventing autoimmunity by inhibiting T-cell activation in peripheral tissues. |
| Source: | HEK293 cells |
| Species: | Canine |
| Tag: | His |
| Formulation: | 1× PBS, pH 8 |
| Proteinlength: | Leu25-Val170 |
| Storage: | For long term storage, the product should be stored at lyophilized state at -20 °C or lower. |
| Reconstitution: | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water. |
| Molecular Mass: | 17.19 kDa |
| Stability: | Upon receiving, the product remains stable for 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. |
| Endotoxin: | <0.001 EU/μg |
| Concentration: | 1 mg/mL |
| Quality Control: | Immobilized canine PDCD1/PD-1/CD279 protein (His tag) binds to anti-PDCD1/PD-1/CD279 antibody with an EC50 of 0.02315 μg/mL. |
| Notes: | Research Use Only. Not for use in clinical procedures. |
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